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AssigneeDigene Corporation
InventorsJames G. Lazar, Joan M. Zakel, Christina M. Strange, Inna R. Williams, Attila T. Lorincz, Abel De La Rosa
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The present invention provides a hybridization method and kit for the detection and measurement of biological molecules. A test sample containing the biological molecules of interest is hybridized with an unlabeled or optionally a detectably labeled complementary biomolecule to form a double-stranded hybrid immobilized to a solid phase. The immobilized hybrid may be detected with an entity which specifically recognizes an RNA:DNA hybrid, followed by analyses and quantification. Therefore, the present invention provides a method and kit to detect and measure biological molecules that is simple to use, highly specific, sensitive, and accurate for screening a plurality of biological molecules.
A method for detecting or quantifying a target nucleic acid on a solid support having a plurality of sample detection sites, comprising:
A method for detecting or quantifying a target nucleic acid on a solid support having a plurality of sample detection sites, comprising:
A method for detecting or quantifying a target nucleic acid on a solid support having a plurality of sample detection sites, comprising:
A method for detecting or quantifying a target nucleic acid on a solid support having a plurality of sample detection sites, comprising:
Dependencies are inferred from the claim text.