US 6,685,965 B1 · PROCESS FOR STABILIZING LEVOGYRE ASCORBIC ACID (LAA), A STABLE AQUEOUS LAA COMPOSITION, A PROCESS FOR PREPARING A STABLE TOPICAL SOLUTION, AN EMULSION, A VITAMIN PRODUCT, AND A METHOD FOR COSMETIC, PHARMACEUTICAL OR NUTRITIONAL TREATMENT

Abstract

The present invention refers to a process for stabilizing LAA in an aqueous medium, which includes the step of contacting the LAA with at least one-compound capable of forming hydrogen bridges with the LAA. In another aspect, the invention relates to a stable aqueous LAA composition which includes, in addition to the ascorbic acid, at least one compound which is linked to the LAA by hydrogen bridges, and to a process for preparing it. The present invention further relates to an emulsion including, in its aqueous phase, at least one compound linked to levogyre ascorbic acid (LAA) by hydrogen bridges. Further according to the present invention a vitamin product is provided, in which a stable LAA composition as described above is contained in organic envelopes which enable a gradual and prolonged release of the LAA into the organism. The vitamin product may further include a compound capable of stimulating the metabolism of the fibroblasts. The present invention further relates to a method for cosmetic, therapeutical or nutritional treatment, which includes the administration of a composition as described above.

Claims15

Dependent claims

A vitamin product, comprising:

an organic envelope;
and
an aqueous complex, inserted in the envelope, the aqueous complex comprising:
water,
levogyre ascorbic acid, and
at least one compound which is linked to the levogyre ascorbic acid by hydrogen bridges to form a stable aqueous complex, wherein said compound is not water wherein said envelope presents a statistic size distribution smaller than 800 microns, and wherein said envelope comprises molecules selected from the group consisting of protein molecules, glucosaminoglycan molecules, polysaccharide molecules, and mixtures thereof.

3 more elements

Dependencies are inferred from the claim text.

Facts

Application

09/420,847Filed 19 Oct 1999 · division

Priority

22 Oct 1997

Granted

3 Feb 2004

Term ends

Not estimatedThe source records don’t support an estimate.

Classification11 codes

A61K 9/0014
Galenical forms characterised by the site of application: skin, i.e. galenical aspects of topical compositions
A61K 9/1652
Organic macromolecular compounds: polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
A61K 9/1658
Organic macromolecular compounds: proteins, e.g. albumin, gelatin
A61K 9/5036
Organic macromolecular compounds: polysaccharides, e.g. gums, alginate; Cyclodextrin

Process for stabilizing levogyre ascorbic acid (laa), a stable aqueous laa composition, a process for preparing a stable topical solution, an emulsion, a vitamin product, and a method for cosmetic, pharmaceutical or nutritional treatment

Life of this patent

Process for stabilizing levogyre ascorbic acid (laa), a stable aqueous laa composition, a process for preparing a stable topical solution, an emulsion, a vitamin product, and a method for cosmetic, pharmaceutical or nutritional treatment

Life of this patent

Abstract

Claims15