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US 6,685,951 B2Granted
Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine
AssigneeR. T. Alamo Ventures I, LLC
InventorNeal R. Cutler
Life of this patent
Estimating the term…
Abstract
The present invention is an improvement in the treatment of migraine headaches. By administering dihydroergotamine as a sublingual spray or aerosol, major limitations of past treatments are circumvented thereby allowing for higher efficacy and fewer side effects of treatment at lower doses.
Claims3
A method of treating migraine comprising:
- the application of a spray to the sublingual mucosa of a patient wherein said spray consists of one active ingredient and one or more inactive ingredients, wherein said active ingredient is dihydroergotamine and wherein at least one of said one or more inactive inactive ingredients is selected from the group consisting of cyclodextrins, dextrans, sugar alcohols and mixtures thereof.
A method of treating migraine comprising:
- the application of an aerosol to the sublingual mucosa of a patient wherein said aerosol consists of one active ingredient and one or more inactive ingredients, wherein said active ingredient is dihydroergotamine and wherein at least one or said one or more inactive ingredients is selected from the group consisting of cyclodextrins, dextrans, sugar alcohols and mixtures thereof.
Dependencies are inferred from the claim text.