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AssigneesCSL Limited, The University of Melbourne, Commonwealth Scientific and Industrial Research Organisation, The Council of the Queensland Institute of Medical Research, The Walter and Eliza Hall Institute of Medical Research
InventorsDavid Charles Jackson, Souravi Ghosh, John Walker
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The present invention provides T helper cells epitopes and compositions for use in inducing an immune response comprising at least one of these epitopes. The epitopes are contained within a peptide sequence selected from the group consisting of SSKTQTHTQQDRPPQPS (SEQ ID NO:1); QPSTELEETRTSRARHS (SEQ ID NO:2); RHSTTSAQRSTHYDPRT (SEQ ID NO:3); PRTSDRPVSYTMNRTRS (SEQ ID NO:4); TRSRKQTSHRLKNIPVH (SEQ ID NO:5); SHQYLVIKLIPNASLIE (SEQ ID NO:6); IGTDNVHYKIMTRPSHQ (SEQ ID NO:7); YKIMTRPSHQYLVIKLI (SEQ ID NO:8); KLIPNASLIENCTKAEL (SEQ ID NO:9); AELGEYEKLLNSVLEPI (SEQ ID NO:10); KLLNSVLEPINQALTLM (SEQ ID NO:11); EPINQALTLMTKNVKPL (SEQ ID NO:12); FAGVVLAGVALGVATAA (SEQ ID NO:13); GVALGVATAAQITAGIA (SEQ ID NO:14); TMQITAGIALHQSNLN (SEQ ID NO:15); GIALHQSNLNAQAIQSL (SEQ ID NO:16); NLNAQAIQSLRTSLEQS (SEQ ID NO:17); QSLRTSLEQSNKAIEEI (SEQ ID NO:18); EQSNKAIEEIREATQET (SEQ ID NO:19); TELLSIFGPSLRDPISA (SEQ ID NO:20); PRYIATNGYLISNFDES (SEQ ID NO:21); CIRGDTSSCARTLVSGT (SEQ ID NO:22); DESSCVFVSESAICSQN (SEQ ID NO:23); TSTIINQSPDKLLTFIA (SEQ ID NO:24); SPDKLLTFIASDTCPLV (SEQ ID NO:25) and SGRRQRRFAGVVLAGVA (SEQ ID NO:26).
A T helper cell epitope, the epitope being contained within a peptide sequence selected from the group consisting of KLIPNASLIENCTKAEL (SEQ ID NO:9);
A composition for use in raising an immune response in an animal, the composition comprising at least one T helper cell epitope, the at least one T helper cell epitope being contained within a peptide sequence selected from the group consisting of KLIPNASLIENCTKAEL (SEQ ID NO:9);
Dependencies are inferred from the claim text.