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US 6,685,934 B1Granted
Recombinant adenoviruses coding for basic fibroblast growth factors (BFGF)
AssigneeAventis Pharma S.A.
InventorsJacques Mallet, Michel Perricaudet, Emmanuelle Vigne, Frédéric Revah, Marc Abitbol, Paul Roustan
Life of this patent
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Abstract
Recombinant adenoviruses comprising a heterologous DNA sequence coding for basic blast growth factors (bFGF), preparation and uses thereof for the treatment and/or prevention of neurodegenerative diseases.
Claims21
An implant comprising an isolated human cell and an extracellular matrix wherein the cell is infected with at least one defective recombinant adenovirus comprising at least one DNA sequence encoding all or an active part of basic fibroblast growth factor, and
- wherein said cell is a retinal cell, glial cell, or nerve cell.
Dependencies are inferred from the claim text.