System and device for preventing restenosis in body vessels
AssigneeThe Penn State Research Foundation
InventorMark Kester
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Abstract
The present invention relates to a system and device for preventing stenosis and/or restenosis after an invasive procedure in a body vessel or cavity having an inner wall surface, the system comprising inserting a device coated with a growth arresting, lipid-derived, bioactive substance at a desired location along the inner wall surface of the body vessel or cavity.
Claims16
A method for preventing restenosis after an invasive procedure in a body vessel or cavity having an inner wall surface, said method comprising:
- inserting a device along the inner wall surface of the body vessel or cavity, said device combined with a growth-arresting, lipid-derived bioactive compound selected from the group consisting of ceramide or derivatives thereof, dimethyl sphingosine, ether-linked diglycerides, ether-linked phosphatidic acids and sphinganines;
- and
- delivering said growth-arresting, lipid-derived bioactive compound to the inner wall surface.
A combination for preventing stenosis and restenosis in a body vessel or cavity having an inner wall surface, said combination comprising a device and a growth-arresting, lipid-derived, bioactive compound selected from the group consisting of ceramide or derivatives thereof, dimethyl sphingosine, ether-linked diglycerides, ether-linked phosphatidic acids and sphinganines.
Dependencies are inferred from the claim text.