Method and an apparatus for providing a constant medicine dose for an inhalic application at low inhalic flow

A device for flow rate limitation at low differential pressures, comprising a housing having at least one aspiration orifice, at least one inhalation orifice, and a flow region with at least one flexible wall disposed therebetween, which region has a cross-section which is adapted to be reduced, as a function of the differential pressure prevailing between said inhalation orifice and said aspiration orifice and of the flexibility of the material of each wall, down to a predefined size for predetermined volumetric maximum inhalation flow, wherein said flow region comprises at least one flow passage having a stratified structure, and wherein each flow passage is formed by a closed wall, a frame-shaped intermediate wall of the same size as the closed wall, and an equally sized wall including said aspiration and inhalation orifices.

A device for flow rate limitation at low differential pressures, comprising a housing having at least one aspiration orifice, at least one inhalation orifice, and a flow region with at least one flexible wall disposed therebetween, which region has a cross-section which is adapted to be reduced, as a function of the differential pressure prevailing between said inhalation orifice and said aspiration orifice and of the flexibility of the material of each wall, down to a predefined size for predetermined volumetric maximum inhalation flow, wherein said flow region comprises at least one flow passage, wherein the flexible material used to form each flow passage consists of a biologically tolerable synthetic material, wherein the cross-section of each flow passage is formed to have opposing large-area passage walls, and wherein at least said large-area passage walls consist of silicone mats.

A device for flow rate limitation at low differential pressures, comprising a housing having at least one aspiration orifice, at least one inhalation orifice, and a flow region with at least one flexible wall disposed therebetween, which region has a cross-section which is adapted to be reduced, as a function of the differential pressure prevailing between said inhalation orifice and said aspiration orifice and of the flexibility of the material of each wall, down to a predefined size for predetermined volumetric maximum inhalation flow, wherein each wall has a chamber section with a bore on its outside at least in the central region between said aspiration and inhalation orifices, with each of the respective bores of the walls communicating with said aspiration orifice through a passage.

A device for flow rate limitation at low differential pressures, comprising a housing having at least one aspiration orifice, at least one inhalation orifice, and a flow region with at least one flexible wall disposed therebetween, which region has a cross-section which is adapted to be reduced, as a function of the differential pressure prevailing between said inhalation orifice and said aspiration orifice and of the flexibility of the material of each wall, down to a predefined size for predetermined volumetric maximum inhalation flow, wherein said flow region comprises at least one flow passage having an annular cross-section, wherein each flow passage is symmetrically disposed in a cylindrical housing at a spacing from the inner walls of said cylinder, between radial retainer disks.

A device for flow rate limitation at low differential pressures, comprising a housing having at least one aspiration orifice, at least one inhalation orifice, and a flow region with at least one flexible wall disposed therebetween, which region has a cross-section which is adapted to be reduced, as a function of the differential pressure prevailing between said inhalation orifice and said aspiration orifice and of the flexibility of the material of each wall, down to a predefined size for predetermined volumetric maximum inhalation flow, wherein said flow region comprises at least one flow passage having an annular cross-section, wherein each annular flow passage is formed by silicone mats.

A device for flow rate limitation at low differential pressures, comprising a housing having at least one aspiration orifice, at least one inhalation orifice, and a flow region with at least one flexible wall disposed therebetween, which region has a cross-section which is adapted to be reduced, as a function of the differential pressure prevailing between said inhalation orifice and said aspiration orifice and of the flexibility of the material of each wall, down to a predefined size for predetermined volumetric maximum inhalation flow, wherein said flow region is formed between a central aspiration orifice and inhalation orifices radially surrounding the central aspiration orifice as well as star-shaped webs extending from a common bottom surface to said at least one flexible wall and forming flow passages.

A device for flow rate limitation at low differential pressures, comprising a housing having at least one aspiration orifice, at least one inhalation orifice, and a flow region with at least one flexible wall disposed therebetween, which region has a cross-section which is adapted to be reduced, as a function of the differential pressure prevailing between said inhalation orifice and said aspiration orifice and of the flexibility of the material of each wall, down to a predefined size for predetermined volumetric maximum inhalation flow, wherein each wall is open on its outside, at least in the central region between said aspiration and inhalation orifices, to the environment, and wherein said device is adapted such that substantially all flow between said aspiration orifice and said inhalation orifice is confined to a flow passage defined by the inside of each wall.