Device and method for monitoring and controlling biologically active fluids

A method for the continuous determination of the concentration of organisms in a fluid present in a line section, where the time-dependent change of at least one metabolite parameter of a metabolite in the line section filled with the fluid is measured by means of at least one data acquisition unit and the concentration of organisms is found from the measured metabolite parameter by a calculation based on a predetermined correlation between the change of the metabolite parameter and the concentration of organisms, wherein the organisms are E. coli, Pseudomonas spec., Lactobacillus spec., Bacillus spec., Leuconostoc spec., clostridium spec., Saccharomyces spec., Sarcina spec., candida spec., Streptococcus, Staphylococcus, Enterobacteniaceae, Enterococci, aerobic spore formers, Pseudomonas aeruginosa, Bacillus subtilis, Micrococcus, Methanobacterium, Methanococcus and Desulfotomaculum.

A method for the continuous determination of the concentration of organisms in a fluid present in a line section, where the time-dependent change of at least one metabolite parameter of a metabolite in the line section filled with the fluid is measured by means of at least one data acquisition unit and the concentration of organisms is found from the measured metabolite parameter by a calculation based on a predetermined correlation between the change of the metabolite parameter and the concentration of organisms, wherein the line is decoupled from a container.

A method for the continuous determination of the concentration of organisms in a fluid present in a line section, where the time-dependent change of at least one metabolite parameter of a metabolite in the line section filled with the fluid is measured by means of at least one data acquisition unit and the concentration of organisms is found from the measured metabolite parameter by a calculation based on a predetermined correlation between the change in of the metabolite parameter and the concentration of organisms, wherein the line is decoupled from a container and the fluid is rotated in the uncoupled line.

A method for the continuous determination of the concentration of organisms in a fluid present in a line section, where the time-dependent change of at least one metabolite parameter of a metabolite in the line section filled with the fluid is measured by means of at least one data acquisition unit and the concentration of organisms is found from the measured metabolite parameter by a calculation based on a predetermined correlation between the change of the metabolite parameter and the concentration of organisms, wherein the measurement is carried out continuously by means of at least two data acquisition units.

A device for determining a concentration of organisms in a fluid, where the device comprises a line section, a data processing system with a program for finding the concentration of organisms on a basis of a predetermined correlation between a change in at least one metabolite parameter of a metabolite and the concentration of organisms, and at least one data acquisition unit which is at least partly disposed in or on the line section, and a sensor.