Process for purifying 6-methoxy omeprazole
OwnerLinda B. Whittall, Grayson Walker Stowell +1inventors
InventorsLinda B. Whittall, Grayson Walker Stowell, Robert R. Whittle
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Abstract
The present invention provides processes for purifying 6-methoxy omeprazole, products using such processes, pharmaceutical formulations using such products, and methods of using such products for gastric acid inhibition.
Claims5
A method of substantially selectively solubilizing without dissolving and recrystallizing 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole or a pharmaceutically acceptable salt, hydrate, or combination thereof from an amount of 5(6)-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole or a pharmaceutically acceptable salt, hydrate, or combination thereof comprising:
- (a) rinsing said amount of 5(6)-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole with a solvent selected from the group consisting of a short carbon chain alcohol solvent and tetrahydrofuran;
- and
- (b) drying the product from step (a).
Dependencies are inferred from the claim text.