Pyrazole antimicrobial agents

A compound having the formula

• wherein
• R1 is selected from the group consisting of H and OR′, wherein R′ is selected from the group consisitng of H and susbtituted or unsubstituted lower alkyl;
• and
• R2 is selected from the group consisting of
• wherein
• R7, R8 and R9 are independently selected from the group consisting of hydroxyl, halogen, nitro, cyano, substituted or unsubstituted (C1-C6)alkyl, (C1-C6)haloalkyl, substituted or unsubstituted (C1-C6)heteroalkyl, (C1-C6)alkoxy, (C1-C6)haloalkoxy, (C1-C6)alkylthio, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, alkanoyl, alkoxycarbonyl, alkylcarbamoyl, sulfonyl, sulfamoyl and NR4R5,
• wherein at least one of R7, R8 and R9 is NR4R5;
• wherein R4 and R5 are independently selected from the group consisting of hydrogen, substituted or unsubstituted (C1-C8)alkyl, substituted or unsubstituted (C1-C8)heteroalkyl, and one or more of R4 and R5 are substituted or unsubstituted (C3-C6)alkyl or substituted or unsubstituted (C3-C6)heteroalkyl combined with the nitrogen atom to which it is attached to form a four-, five-, six- or seven-membered ring optionally having additional substituents selected from substituted or unsubstituted (C1-C8)alkyl, substituted or unsubstituted (C1-C8)heteroalkyl and substituted or unsubstituted phenyl;
• wherein at least one of R4 and R5 is selected from the group consisting of(C1-C8)alkyl and (C1-C8)heteroalkyl, comprising a substituent selected from substituted or unsubstituted aryl and substituted or unsubstituted heterocycloalkyl;
• and
• R3 is substituted or unsubstituted aryl.