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US 6,673,915 B1Granted
Nucleic acid encoding monocyte chemotactic protein 4
AssigneeThe General Hospital Corporation
InventorsAndrew D. Luster, Eduardo A. Garcia-Zepeda, Mindy N. Sarafi
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Abstract
Substantially pure nucleic acid molecules encoding the monocyte chemotactic proteins MCP-4 and MCP-5. These molecules and the polypeptides they encode are useful in treating diseases or conditions that: (1) are exacerbated by a local immune response, (2) would benefit from a local immune response, or (3) are caused by infectious agents that gain entry to mammalian cells via the chemokine receptors bound by MCP-4 or MCP-5.
Claims4
A substantially pure nucleic acid molecule comprising nucleotides 35-331 of SEQ ID NO:
- 1, wherein said nucleic acid molecule encodes a monocyte chemotactic protein (MCP)-4 polypeptide.
Dependencies are inferred from the claim text.