Sodium ion-driven chloride /bi-carbonate exchanger
AssigneesJCR Pharmaceuticals Co., Ltd., Susumu Seino
InventorsSusumu Seino, Hideki Yano, Changzheng Wang
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Abstract
The present invention discloses DNAs comprising nucleotide sequences set forth as SEQ ID NO:1 or NO:3 encoding Na+-driven Cl—/HCO3— exchanger, proteins comprising amino acid sequences set forth as SEQ ID NO:2 or NO:4, and their homologous proteins comprising an amino acid sequence having deletion, substitution, addition or insertion amino acids, which proteins, when expressed in a cell, functions as Na+-driven Cl—/HCO3— exchanger, and cells in which the proteins exogenously expressed.
Claims1
An isolated protein comprising the amino acid sequence set forth as SEQ ID NO:2 or NO:4 in the sequence listing.
Dependencies are inferred from the claim text.