Platinum derivative pharmaceutical formulations
AssigneePharmacia Italia S.p.A.
InventorsSara Lauria, Alessandro Martini, Cristina Ciocca
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Abstract
The present invention relates to novel stable solution formulations comprising oxaliplatin alone or in combination with irinotecan (CPT-11), an effective stabilizing amount of lactic acid and/or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier. A method for manufacturing such formulations ready for administration and their use in the antitumor therapy are also within the scope of the invention.
Claims14
A combined pharmaceutical formulation comprising oxaliplatin and irinotecan hydrochloride as active ingredients in fixed weight ratios, an effective stabilizing amount of lactic acid or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.