Treatment of systemic lupus erythematosis
AssigneeWisconsin Alumni Research Foundation
InventorsHector F. DeLuca, Margherita T. Cantorna, Jean Humpal-Winter
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Abstract
A method of treating SLE symptoms of an SLE patient comprising administering to an SLE patient an amount of vitamin D compound effective to reduce symptoms and observing a reduction in symptoms is disclosed.
Claims10
A method of treating proteinuria symptoms in an SLE patient comprising orally administering a dose of vitamin D compound effective to reduce or eliminate proteinuria to an SLE patient with a calcium intake level of at least 800 mg/day/160 patient wherein the vitamin D compound is selected from the group of 1,25-dihydroxyvitamin D3, 19-nor-1,25-dihydroxyvitamin D2, 19-nor-21-epi-1,25-dihydroxyvitamin D3, 1,25-dihydroxy-24-homo-22-dehydro-22E vitamin D3, and 19-nor-1,25-dihydroxy-24-homo-22-dehydro-22E-vitamin D3.
A method of treating swollen lymph node symptoms in an SLE patient comprising orally administering a dose of vitamin D compound effective to reduce or eliminate swollen lymph nodes to an individual susceptible to SLE patient with a calcium intake level of at least 800 mg/day/160 patient wherein the vitamin D compound is selected from the group of 1,25-dihydroxyvitamin D3, 19-nor-1,25-dihydroxyvitamin D2, 19-nor-21-epi-1,25-dihydroxyvitamin D3, 1,25-dihydroxy-24-homo-22-dehydro-22E vitamin D3, and 19-nor-1,25-dihydroxy-24-homo-22-dehydro-22E-vitamin D3.
A method of treating SLE symptoms in individuals susceptible to SLE, comprising orally administering an amount of vitamin D compound effective to prevent symptoms in the individual to an individual susceptible to SLE with a calcium intake level of at least 800 mg/day/160 patient wherein the vitamin D compound is selected from the group of 1,25-dihydroxyvitamin D3, 19-nor-1,25-dihydroxyvitamin D2, 19-nor-21-epi-1,25-dihydroxyvitamin D3, 1,25-dihydroxy-24-homo-22-dehydro-22E vitamin D3, and 19-nor-1,25-dihydroxy-24-homo-22-dehydro-22E-vitamin D3.
Dependencies are inferred from the claim text.