Rapid methods and kits for detection and semi-quantitation of anti-adenovirus antibody
AssigneeCell Genesys, Inc.
InventorsDavid Charlton, Daniel R. Henderson
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Abstract
Methods for rapid detection and/or semi-quantitation of anti-adenovirus antibody are disclosed. Anti-adenovirus antibody is detected using a device comprising a membrane with adsorbed antigen which specifically binds anti-adenovirus antibody and an absorbent pad which is contacted with the membrane. By consolidating detection reactions in a confined location and eliminating the need to manually remove input reagents, detection and semi-quantitation is achieved rapidly and conveniently. The invention also provides kits and devices for detection and/or semi-quantitation of anti-adenovirus antibodies.
Claims16
A kit for rapid detection or semi-quantitation of anti-adenovirus antibody in a sample, comprising a membrane, an absorbent pad in contact with the output surface of the membrane, and intact, whole adenovirus adsorbed to said membrane that specifically binds to anti-adenovirus antibody, said kit in suitable packaging.
A kit for detection or semi-quantitation of anti-adenovirus antibody in a sample, comprising nitrocellulose paper and a cellulose-based pad in contact with the output surface of the nitrocellulose paper, wherein the nitrocellulose paper and cellulose-based material are housed in a sample well, intact whole adenovirus-5 adsorbed on said nitrocellulose paper, HEPES 5 buffer, gold-conjugated protein A, and human IgG, said kit in suitable packaging.
Dependencies are inferred from the claim text.