Established cell line of microglia
AssigneeJapan Science and Technology Corporation
InventorMakoto Sawada
Life of this patent
Estimating the term…
Abstract
The present invention relates to an established cell line of microglia having the following properties: (a) form: having a macrophage-like or globular form in the presence of granulocyte-macrophage colony-stimulating factor. and in the absence of said factor, a branched form similar to branched microglia present in the brain, or both of the above forms; (b) functional characteristics: having specific affinity for the brain, and having a strong phagocytic ability; and (c) cell growth ability: growing depending on granulocyte-macrophage colony-stimulating factor. In particular, cell lines FERM BP-7061 and FERM BP-7062.
Claims2
A biologically pure cell line of microglia having all identifying characteristics of the cell line Ra2 (FERM BP-7061) which is capable of passing through blood-brain barrier.
A biologically pure cell line of microglia having all identifying characteristics of the cell line GMI-R1 FERM BP-7062) which is capable of passing through blood-brain barrier.
Dependencies are inferred from the claim text.