Polymer, in vivo degradable material, and use
AssigneeNof Corporation
InventorsAtsuhiko Ogura, Hiroshi Iwasaki, Shinji Tanaka
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Abstract
A polymer having a satisfactory balance between in vivo degradability and satisfactory mechanical properties, which is an A1BA2 type polymer comprising a segment A1 and a segment A2 each having a modified amino acid and a segment B consisting of polyethylene glycol with a number-average molecular weight of 8000 or higher bonded at one end to the segment A1 and at the other end to the segment A2, and has a number-average molecular weight of 10000 to 600000; an in vivo degradable material which comprises the polymer; and a film for preventing tissue adhesion, an artificial dura mater, a suture, an implant preparation, or a sustained-release drug base each comprising the degradable material.
Claims10
An A1BA2-type polymer having a number average molecular weight of 10000 to 600000, wherein the polymer is composed of a segment A1 and a segment A2 each including hydrophobic poly modified amino acids, and a segment B composed of polyethylene glycol with a number average molecular weight of 8000 or higher, the segment A1 being bonded to one end of the segment B while the segment A2 is bonded to the other end of the segment B, wherein the total number average molecular weight of the segment A1 and the segment A2 is from 4000 to 20000.
Dependencies are inferred from the claim text.