US 6,673,337 B2Granted

Compositions containing alpha-2-adrenergic agonist components

AssigneeAllergan, Inc.

InventorsOrest Olejnik, Edward D. S. Kerslake

Life of this patent

Estimating the term…

Abstract

Compositions useful for improving effectiveness of alpha-2-adrenergic agonist components include carrier components, alpha-2-adrenergic agonist components, solubility enhancing components which aid in solubilizing the alpha-2-adrenergic agonist components. In one embodiment, the alpha-2-adrenergic agonist components include alpha-2-adrenergic agonists. In another embodiment, the solubility enhancing components include carboxymethylcellulose.

Claims10

Dependent claims

A therapeutically effective ophthalmic composition comprising:

an alpha-2-adrenergic agonist component in an amount effective to provide a therapeutic benefit to a patient to whom the composition is administered;
and
a solubility enhancing component other than a cyclodextrin in an amount effective to increase the solubility of the alpha-2-adrenergic agonist component in the composition relataive to the solubility of an identical alpha-2-adrenergic agonist component in a similar composition without the solubility enhancing component.

Dependencies are inferred from the claim text.

Facts

Application: 10/299,386Filed 19 Nov 2002 · division
Priority: 14 Jul 2000
Published: US 2003/0087893 A18 May 2003
Granted: 6 Jan 2004
Term ends: Not estimatedThe source records don’t support an estimate.

Classification12 codes

A61K 31/734
Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers,…:…
A61K 9/0048
Galenical forms characterised by the site of application: eye, e.g. artificial tears
A61K 31/498
Having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines: pyrazines or piperazines…
A61K 31/715
Carbohydrates; Sugars; Derivatives thereof: polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic…

Family

Application60/218,200Us provisional application · filed 14 Jul 2000
Application09/904,018Parent of this division · filed 10 Jul 2001
US 2003/0087893 A1Pre-grant publication · published 8 May 2003
US 2002/0032201 A1Published application
US 6,627,210 B2Related patent
US 6,673,337 B2This patent

From the US filing history. Foreign family members aren’t listed.

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Abstract

Facts

Application

10/299,386Filed 19 Nov 2002 · division

Priority

14 Jul 2000

Published

US 2003/0087893 A18 May 2003

Granted

6 Jan 2004

Term ends

Not estimatedThe source records don’t support an estimate.

Classification12 codes

A61K 31/734
Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers,…:…
A61K 9/0048
Galenical forms characterised by the site of application: eye, e.g. artificial tears
A61K 31/498
Having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines: pyrazines or piperazines…
A61K 31/715
Carbohydrates; Sugars; Derivatives thereof: polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic…

Family

Application60/218,200Us provisional application · filed 14 Jul 2000

Application09/904,018Parent of this division · filed 10 Jul 2001

US 2003/0087893 A1Pre-grant publication · published 8 May 2003

US 2002/0032201 A1Published application

US 6,627,210 B2Related patent

US 6,673,337 B2This patent

From the US filing history. Foreign family members aren’t listed.