Multivalent antigen-binding proteins
AssigneeUnilever Patent Holdings B.V.
InventorsLeon Gerardus Frenken, Steven Howell, Adrianus Marinus Ledeboer, Cornelis P van der Logt
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Abstract
A multivalent antigen binding protein comprises a single polypeptide chain comprising, in series, two or more single domain binding units which are preferably heavy chain variable domains derived from an immunoglobulin naturally devoid of light chains. Methods for their production and uses thereof, in particular for diagnosis, immunoassay and purification methods are disclosed.
Claims7
A multivalent antigen binding protein comprising a single polypeptide chain comprising two or more single domain binding units, which are connected directly in series, wherein the single domain binding units are heavy chain variable domains obtained from an immunoglobulin naturally devoid of light chains.
Dependencies are inferred from the claim text.