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US 6,670,166 B1Granted
Arthropod protein disulfide isomerases
AssigneeE. I. Du Pont de Nemours and Company
InventorsRebecca E. Cahoon, Rafael Herrmann, Albert L. Lu
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Abstract
This invention relates to an isolated nucleic acid fragment encoding protein disulfide isomerase. The invention also relates to the construction of a chimeric gene encoding all or a portion of the protein disulfide isomerase, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the protein disulfide isomerase in a transformed host cell.
Claims16
An isolated polynucleotide comprising:
- (a) a nucleic acid sequence encoding a polypeptide having protein disulfide isomerase activity, wherein the polypeptide has an amino acid sequence of at least 80% sequence identity based on Clustal method of alignment when compared to one of SEQ ID NO:16 or 18;
- or
- (b) a complement of the nucleic acid sequence wherein the complement and nucleic acid sequence consist of the same number of nucleotides and are 100% complementary.
Dependencies are inferred from the claim text.