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US 6,669,966 B1Granted
Compositions for facilitating skin growth and methods and articles using same
AssigneeMarantech Holding, LLC
InventorMarvin S. Antelman
Life of this patent
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AssigneeMarantech Holding, LLC
InventorMarvin S. Antelman
Estimating the term…
Skin-growth-enhancing compounds and compositions including a therapeutically effective amount of at least one electron active compound, or a pharmaceutically acceptable derivative thereof, that has at least two polyvalent cations, at least one of which has a first valence state and at least one of which has a second, different valence state. Preferred compounds include Bi(III,V) oxide, Co(II,III) oxide, Cu(I,III) oxide, Fe(II,III) oxide, Mn(II,III) oxide, and Pr(III,IV) oxide, and Ag(I,III) oxide, or a combination thereof. These compounds may be in a crystalline state having metallic cations of two different valences, or electronic states, in the inorganic crystal. Also included are articles containing such compositions, such as wound dressings, and methods for facilitating or enhancing skin growth using these compounds, compositions, and articles, such as for the treatment or management of burns or skin grafts.
A method for facilitating or enhancing growth of a patient's skin, which comprises administering at least one electron active compound that has at least two polyvalent cations, at least one of which has a first valence state and at least one of which has a second different valence state, said at least one electron active compound being administered in an amount and for a period of time which is therapeutically effective to facilitate or enhance skin growth, and wherein the electron active compound comprises at least one of Bi(III,V) oxide, Co(II,III) oxide, Cu(I,III) oxide, Fe(II,III) oxide, Mn(II,III) oxide, or Pr(III,IV) oxide.
A skin-growth-enhancing composition comprising:
A dressing comprising at least one electron active compound, the electron active compound having at least two polyvalent cations, at least one of which has a first valence state and at least one of which has a second different valence state, wherein the electron active compound comprises at least one of Bi(III,V) oxide, Co(II,III) oxide, Cu(I,III) oxide, Mn(II,III) oxide, or Pr(III,IV) oxide.
A method treating or managing one or more conditions, which comprises topically administering to a patient at least one dressing comprising at least one electron active compound, the electron active compound having at least two polyvalent cations, at least one of which has a first valence state and at least one of which has a second different valence state, wherein the electron active compound comprises at least one of Bi(III,V) oxide, Co(II,III) oxide, Cu(I,III) oxide, Mn(II,III) oxide, or Pr(III,IV) oxide, and wherein the condition comprises at least one of a wound, a burn, a lesion, an ulcer, a sore, a boil, a wart, or combination thereof.
Dependencies are inferred from the claim text.