US 6,669,939 B1 · (Poly)peptides which represent the epitopes of the human herpes virus type 8

Abstract

The present invention relates to (poly)peptides, which are recognized by anti-HHV8 antibodies of HHV-8 infected patients, whereby these (poly)peptides are not naturally occurring HHV-8 proteins. The present invention further relates to polymers, comprising at least two identical or different peptides according to the invention as well as conjugates, comprising said peptides and/or polymers thereof. Furthermore, this invention provides mixtures, comprising said peptides and/or polymers thereof, which are used to detect anti-HHV-8 antibodies with high sensitivity and specificity. In addition, the present invention relates to a diagnostic kit, comprising said peptides, polymers and/or mixtures thereof, which can be used for the detection of anti-HHV-8 antibodies and for the diagnosis of an HHV-8 infection, respectively.

Claims10

Dependent claims

A peptide mixture consisting essentially of a mixture of

peptides consisting of the amino acid sequences of SEQ ID Nos.:
5 and 8,
wherein either peptide is not a full length HHV-8 protein as coded by the HHV-8 genome and the peptide mixture is recognized by anti-HHV-8 antibodies of HHV-8-infected patients.

Dependencies are inferred from the claim text.

(Poly)peptides which represent the epitopes of the human herpes virus type 8

Life of this patent

(Poly)peptides which represent the epitopes of the human herpes virus type 8

Life of this patent

Abstract

Claims10