US 6,665,557 B1 · Sprectroscopic and time-resolved optical methods and apparatus for imaging objects in turbed media

A method of imaging an object in medium, wherein said object is a tumor and said turbid medium is a tissue, said method comprising the steps of:

(a) illuminating at least a portion of the turbid medium with substantially monochromatic light of a first wavelength, said illuminated portion of the turbid medium comprising the object, said first wavelength being selected from the group consisting of a wavelength in the range of 940-1010 nm, a wavelength in the range of 1120-1240 nm, and a wavelength in the range of 1400-1500 nm;
(b) wherein each of the turbid medium and the object has a resonance wavelength for an optical property, wherein the respective resonance wavelengths for the turbid medium and the object are different for said optical property and wherein said substantially monochromatic light of said first wavelength is equal in wavelength to the resonance wavelength for said optical property of one of the turbid medium and the object;
(c) using at least a portion of the light emergent from the turbid medium to form an image of the object in the turbid medium.

A method of imaging an object in a turbid medium, said method comprising the steps of:

(a) illuminating at least a portion of the turbid medium with substantially monochromatic light of a first wavelength, said illuminated portion of the turbid medium comprising the object;
(b) wherein each of the turbid medium and the object has a resonance wavelength for an optical property, wherein the respective resonance wavelengths for the turbid medium and the object are different, wherein said substantially monochromatic light of said first wavelength is equal in wavelength to the resonance wavelength for said optical property of one of the turbid medium and the object and wherein said first wavelength is selected from the group consisting of a wavelength in the range of 940-1010 nm, a wavelength in the range of 1120-1240 nm, and a wavelength in the range of 1400-1500 nm;
(c) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said first wavelength;
(d) illuminating at least a portion of the turbid medium with substantially monochromatic light of a second wavelength, said illuminated portion of the turbid medium comprising the object;
(e) wherein said substantially monochromatic light of said second wavelength is not equal in wavelength to the resonance wavelength for said optical property of either the turbid medium or the object;
(f) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said second wavelength;
and
(g) using the light detected in step (c) to form a resonant image and that detected in step (f) to form a non-resonant image of the object in the turbid medium.

5 more elements

A method of imaging an object in a turbid medium, said method comprising the steps of:

(a) illuminating at least a portion of the turbid medium with substantially monochromatic light of a first wavelength, said illuminated portion of the turbid medium comprising the object, wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said first wavelength comprises a ballistic component, a snake component and a diffuse component;
(b) wherein each of the turbid medium and the object has a resonance wavelength for an optical property, wherein the respective resonance wavelengths for the turbid medium and the object are different and wherein said substantially monochromatic light of said first wavelength is equal in wavelength to the resonance wavelength for said optical property of one of the turbid medium and the object;
(c) preferentially selecting from the emergent light the ballistic and snake components thereof;
(d) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said first wavelength;
(e) illuminating at least a portion of the turbid medium with substantially monochromatic light of a second wavelength, said illuminated portion of the turbid medium comprising the object, wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said second wavelength comprises a ballistic component, a snake component and a diffuse component:
(f) preferentially selecting from the emergent light the ballistic and snake components thereof;
(g) wherein said substantially monochromatic light of said second wavelength is not equal in wavelength to the resonance wavelength for said optical property of either the turbid medium or the object;
(h) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said second wavelength;
and
(i) using the light detected in step (d) to form a resonant image and that detected in step (h) to form a non-resonant image of the object in the turbid medium, wherein said using step comprises using a ratio of the resonant and non-resonant images to form an image of the object in the turbid medium.

7 more elements

A method of imaging an object in a turbid medium, wherein the image is a 3-D image, said method comprising the steps of:

(a) illuminating at least a portion of the turbid medium with substantially monochromatic light of a first wavelength, said illuminated portion of the turbid medium comprising the object, wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said first wavelength comprises a ballistic component, a snake component and a diffuse component;
(b) wherein each of the turbid medium and the object has a resonance wavelength for an optical property, wherein the respective resonance wavelengths for the turbid medium and the object are different and wherein said substantially monochromatic light of said first wavelength is equal in wavelength to the resonance wavelength for said optical property of one of the turbid medium and the object;
(c) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said first wavelength, wherein said detecting step comprises determining the intensity of the diffuse component at a plurality of points in time;
(d) illuminating at least a portion of the turbid medium with substantially monochromatic light of a second wavelength, said illuminated portion of the turbid medium comprising the object, wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said second wavelength comprises a ballistic component, a snake component and a diffuse component;
(e) wherein said substantially monochromatic light of said second wavelength is not equal in wavelength to the resonance wavelength for said optical property of either the turbid medium or the object;
(f) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said second wavelength, wherein said detecting step comprises determining the intensity of the diffuse component at a plurality of points in time;
and
(g) using the light detected in step (c) to form a resonant image and that detected in step (f) to form a non-resonant image of the object in the turbid medium, wherein said using step comprises using said pluralities of intensity determinations and a mathematical inversion algorithm to form a 3-D image of the object in the turbid medium.

5 more elements

A method of imaging an object in a turbid medium, said method comprising the steps of:

(a) illuminating at least a portion of the turbid medium with substantially monochromatic light of a first wavelength, said illuminated portion of the turbid medium comprising the object, wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said first wavelength comprises a ballistic component, a snake component and a diffuse component;
(b) wherein each of the turbid medium and the object has a resonance wavelength for an optical property, wherein the respective resonance wavelengths for the turbid medium and the object are different and wherein said substantially monochromatic light of said first wavelength is equal in wavelength to the resonance wavelength for said optical property of one of the turbid medium and the object;
(c) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said first wavelength, wherein said detecting step comprises determining the intensity of the diffuse component at a plurality of points in time;
(d) illuminating at least a portion of the turbid medium with substantially monochromatic light of a second wavelength, said illuminated portion of the turbid medium comprising the object, wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said second wavelength comprises a ballistic component, a snake component and a diffuse component;
(e) wherein said substantially monochromatic light of said second wavelength is not equal in wavelength to the resonance wavelength for said optical property of either the turbid medium or the object;
(f) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said second wavelength, wherein said detecting step comprises determining the intensity of the diffuse component at a plurality of points in time;
and
(g) using the light detected in step (c) to form a resonant image and that detected in step (f) to form a non-resonant image of the object in the turbid medium, wherein said using step comprises using said pluralities of intensity determinations and a mathematical inversion algorithm to form an image of the object in the turbid medium;
(h) wherein said illuminating and detecting steps are performed in a transmission geometry.

6 more elements

A method of imaging an object in a turbid medium, said method comprising the steps of:

(a) illuminating at least a portion of the turbid medium with substantially monochromatic light of a first wavelength, said illuminated portion of the turbid medium comprising the object, wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said first wavelength comprises a ballistic component, a snake component and a diffuse component;
(b) wherein each of the turbid medium and the object has a resonance wavelength for an optical property, wherein the respective resonance wavelengths for the turbid medium and the object are different and wherein said substantially monochromatic light of said first wavelength is equal in wavelength to the resonance wavelength for said optical property of one of the turbid medium and the object;
(c) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said first wavelength, wherein said detecting step comprises determining the intensity of the diffuse component at a plurality of points in time and at a plurality of locations around the turbid medium;
(d) illuminating at least a portion of the turbid medium with substantially monochromatic light of a second wavelength, said illuminated portion of the turbid medium comprising the object, wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said second wavelength comprises a ballistic component, a snake component and a diffuse component;
(e) wherein said substantially monochromatic light of said second wavelength is not equal in wavelength to the resonance wavelength for said optical property of either the turbid medium or the object;
(f) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said second wavelength, wherein said detecting step comprises determining the intensity of the diffuse component at a plurality of points in time and at a plurality of locations around the turbid medium;
and
(g) using the light detected in step (c) to form a resonant image and that detected in step (f) to form a non-resonant image of the object in the turbid medium, wherein said using step comprises using said pluralities of intensity determinations and a mathematical inversion algorithm to form an image of the object in the turbid medium.

5 more elements

A method of imaging an object in a turbid medium, wherein the turbid medium is a human body part, said method comprising the steps of:

(a) illuminating at least a portion of the turbid medium with substantially monochromatic light of a first wavelength, said illuminated portion of the turbid medium comprising the object;
(b) wherein each of the turbid medium and the object has a resonance wavelength for an optical property, wherein the respective resonance wavelengths for the turbid medium and the object are different and wherein said substantially monochromatic light of said first wavelength is equal in wavelength to the resonance wavelength for said optical property of one of the turbid medium and the object;
(c) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said first wavelength;
(d) illuminating at least a portion of the turbid medium with substantially monochromatic light of a second wavelength, said illuminated portion of the turbid medium comprising the object;
(e) wherein said substantially monochromatic light of said second wavelength is not equal in wavelength to the resonance wavelength for said optical property of either the turbid medium or the object;
(f) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said second wavelength;
and
(g) using the light detected in step (c) to form a resonant image and that detected in step (f) to form a non-resonant image of the object in the turbid medium;
(h) wherein the light emergent from the turbid medium following illumination with each of said substantially monochromatic light of said first wavelength and said substantially monochromatic light of said second wavelength comprises a ballistic component, a snake component and a diffuse component, wherein each of said detecting steps comprises determining the intensity of the diffuse component at a plurality of points in time and wherein said using step comprises using said pluralities of intensity determinations and a mathematical inversion algorithm to form an image of the object in the turbid medium.

6 more elements

A method of imaging an object in a turbid medium, said method comprising the steps of:

(a) illuminating at least a portion of the turbid medium with substantially monochromatic light of a first wavelength, said illuminated portion of the turbid medium comprising the object;
(b) wherein each of the turbid medium and the object has a resonance wavelength for an optical property, wherein the respective resonance wavelengths for the turbid medium and the object are different and wherein said substantially monochromatic light of said first wavelength is equal in wavelength to the resonance wavelength for said optical property of one of the turbid medium and the object;
(c) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said first wavelength;
(d) illuminating at least a portion of the turbid medium with substantially monochromatic light of a second wavelength, said illuminated portion of the turbid medium comprising the object;
(e) wherein said substantially monochromatic light of said second wavelength is not equal in wavelength to the resonance wavelength for said optical property of either the turbid medium or the object;
(f) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said second wavelength;
and
(g) using the light detected in step (c) to form a resonant image and that detected in step (f) to form a non-resonant image of the object in the turbid medium;
(h) wherein the turbid medium is a human breast, wherein one and only one of said first wavelength and said second wavelength is a wavelength selected from the group consisting of 950-980 nm and 1150-1350 nm, wherein the light emergent from the turbid medium following illumination with each of said substantially monochromatic light of said first wavelength and said substantially monochromatic light of said second wavelength comprises a ballistic component, a snake component and a diffuse component, wherein each of said detecting steps comprises determining the intensity of the diffuse component at a plurality of points in time and wherein said using step comprises using said pluralities of intensity determinations and a mathematical inversion algorithm to form an image of the object in the turbid medium.

6 more elements

A method of imaging an object in a turbid medium, said method comprising the steps of:

(a) illuminating at least a portion of the turbid medium with substantially monochromatic light of a first wavelength, said illuminated portion of the turbid medium comprising the object, wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said first wavelength comprises a ballistic component, a snake component and a diffuse component;
(b) wherein each of the turbid medium and the object has a resonance wavelength for an optical property, wherein the respective resonance wavelengths for the turbid medium and the object are different and wherein said substantially monochromatic light of said first wavelength is equal in wavelength to the resonance wavelength for said optical property of one of the turbid medium and the object;
(c) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said first wavelength, wherein said detecting step comprises determining the intensity of the diffuse component at a plurality of points in time, wherein said determining step comprises obtaining a sequence of 2-D time-sliced images using different temporal slices of the transmitted light using the ballistic, snake and diffuse photons, said different temporal slices being obtained by positioning the time gate at different points in time;
(d) illuminating at least a portion of the turbid medium with substantially monochromatic light of a second wavelength, said illuminated portion of the turbid medium comprising the object, wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said second wavelength comprises a ballistic component, a snake component and a diffuse component;
(e) wherein said substantially monochromatic light of said second wavelength is not equal in wavelength to the resonance wavelength for said optical property of either the turbid medium or the object;
(f) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said second wavelength, wherein said detecting step comprises determining the intensity of the diffuse component at a plurality of points in time, wherein said determining step comprises obtaining a sequence of 2-D time-sliced images using different temporal slices of the transmitted light using the ballistic, snake and diffuse photons, said different temporal slices being obtained by positioning the time gate at different points in time;
and
(g) using the light detected in step (c) to form a resonant image and that detected in step (f) to form a non-resonant image of the object in the turbid medium, wherein said using step comprises using said pluralities of intensity determinations and a mathematical inversion algorithm to form an image of the object in the turbid medium.

5 more elements

A method of imaging an object in a turbid medium, said method comprising the steps of:

(a) illuminating at least a portion of the turbid medium with substantially monochromatic light of a first wavelength, said illuminated portion of the turbid medium comprising the object, wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said first wavelength comprises a ballistic component, a snake component and a diffuse component;
(b) wherein each of the turbid medium and the object has a resonance wavelength for an optical property, wherein the respective resonance wavelengths for the turbid medium and the object are different and wherein said substantially monochromatic light of said first wavelength is equal in wavelength to the resonance wavelength for said optical property of one of the turbid medium and the object;
(c) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said first wavelength, wherein said detecting step comprises determining the intensity of the diffuse component at a plurality of points in time, wherein said determining step comprises obtaining a sequence of 2-D time-sliced images using different temporal slices of the back-propagating light including the ballistic, snake and diffuse photons, said different temporal slices being obtained by positioning the gate at different points in time;
(d) illuminating at least a portion of the turbid medium with substantially monochromatic light of a second wavelength, said illuminated portion of the turbid medium comprising the object, wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said second wavelength comprises a ballistic component, a snake component and a diffuse component;
(e) wherein said substantially monochromatic light of said second wavelength is not equal in wavelength to the resonance wavelength for said optical property of either the turbid medium or the object;
(f) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said second wavelength, wherein said detecting step comprises determining the intensity of the diffuse component at a plurality of points in time wherein said determining step comprises obtaining a sequence of 2-D time-sliced images using different temporal slices of the back-propagating light including the ballistic, snake and diffuse photons, said different temporal slices being obtained by positioning the gate at different points in time;
and
(p) using the light detected in step (c) to form a resonant image and that detected in step (f) to form a non-resonant image of the object in the turbid medium wherein said using step comprises using said pluralities of intensity determinations and a mathematical inversion algorithm to form an image of the object in the turbid medium.

5 more elements

A method of imaging an object in a turbid medium, wherein the turbid medium is the prostate, said method comprising the steps of:

(a) illuminating at least a portion of the turbid medium with substantially monochromatic light of a first wavelength, said illuminated portion of the turbid medium comprising the object, wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said first wavelength comprises a ballistic component, a snake component and a diffuse component;
(b) wherein each of the turbid medium and the object has a resonance wavelength for an optical property, wherein the respective resonance wavelengths for the turbid medium and the object are different and wherein said substantially monochromatic light of said first wavelength is equal in wavelength to the resonance wavelength for said optical property of one of the turbid medium and the object;
(c) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said first wavelength;
(d) illuminating at least a portion of the turbid medium with substantially monochromatic light of a second wavelength, said illuminated portion of the turbid medium comprising the object wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said second wavelength comprises a ballistic component, a snake component and a diffuse component;
(e) wherein said substantially monochromatic light of said second wavelength is not equal in wavelength to the resonance wavelength for said optical property of either the turbid medium or the object;
(f) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said second wavelength;
and
(g) using the light detected in step (c) to form a resonant image and that detected in step (f) to form a non-resonant image of the object in the turbid medium;
(h) wherein each of said detecting steps comprises determining the intensity of the diffuse component at a plurality of points in time by obtaining a sequence of 2-D time-sliced images using different temporal slices of the back-propagating light including the ballistic, snake and diffuse photons, said different temporal slices being obtained by positioning the gate at different points in time and wherein said using step comprises using said pluralities of intensity determinations and a mathematical inversion algorithm to form an image of the object in the turbid medium, said image being a 3-D image, said 3-D image being reconstructed using a difference of wavelengths that are resonant and non-resonant with certain optical properties of the object enabling construction of a 3-D map of said optical property.

6 more elements

An apparatus for imaging an object in a turbid medium, said apparatus comprising:

(a) first illuminating means for illuminating at least a portion of the turbid medium with substantially monochromatic light of a first wavelength, said illuminated portion of the turbid medium comprising the object, wherein said first wavelength is selected from the group consisting of a wavelength in the range of 940-1010 nm, a wavelength in the range of 1120-1240 nm and a wavelength in the range of 1400-1500 nm;
(b) wherein each of the turbid medium and the object has a resonance wavelength for an optical property, wherein the respective resonance wavelengths for the turbid medium and the object are different and wherein said substantially monochromatic light of said first wavelength is equal in wavelength to the resonance wavelength for said optical property of one of the turbid medium and the object;
(c) second illuminating means for illuminating at least a portion of the turbid medium with substantially monochromatic light of a second wavelength, said illuminated portion of the turbid medium comprising the object;
(d) wherein said substantially monochromatic light of said second wavelength is not equal in wavelength to the resonance wavelength for said optical property of either the turbid medium or the object;
(e) means for detecting at least a portion of the light emergent from the turbid medium following illumination by said first illuminating means and following illumination by said second illuminating means;
and
(f) means for using the light detected by said detecting means to form an image of the object in the turbid medium.

4 more elements

An apparatus for imaging an object in a turbid medium, said apparatus comprising:

(a) first illuminating means for illuminating at least a portion of the turbid medium with substantially monochromatic light of a first wavelength said illuminated portion of the turbid medium comprising the object wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said first wavelength comprises a ballistic component, a snake component and a diffuse component;
(b) wherein each of the turbid medium and the object has a resonance wavelength for an optical property, wherein the respective resonance wavelengths for the turbid medium and the object are different and wherein said substantially monochromatic light of said first wavelength is equal in wavelength to the resonance wavelength for said optical property of one of the turbid medium and the object;
(c) second illuminating means for illuminating at least a portion of the turbid medium with substantially monochromatic light of a second wavelength, said illuminated portion of the turbid medium comprising the object, wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said second wavelength comprises a ballistic component, a snake component and a diffuse component;
(d) wherein said substantially monochromatic light of said second wavelength is not equal in wavelength to the resonance wavelength for said optical property of either the turbid medium or the object;
(e) means for detecting at least a portion of the light emergent from the turbid medium following illumination by said first illuminating means and following illumination by said second illuminating means, wherein said detecting means comprises means for determining the intensity of the diffuse component at a plurality of points in time;
and
(f) means for using the light detected by said detecting means to form an image of the object in the turbid medium, wherein said using means comprises means for using said pluralities of intensity determinations and a mathematical inversion algorithm to form an image of the object in the turbid medium.

4 more elements

A method of imaging an object in a turbid medium, said method comprising the steps of:

(a) illuminating at least a portion of the turbid medium with substantially monochromatic light of a first wavelength, said illuminated portion of the turbid medium comprising the object, wherein said first wavelength is selected from the group consisting of a wavelength in the range of 940-1010 nm a wavelength in the range of 1120-1240 nm and a wavelength in the range of 1400-1500 nm;
(b) wherein each of the turbid medium and the object has a resonance wavelength for an optical property, wherein the respective resonance wavelengths for the turbid medium and the object are different and wherein said substantially monochromatic light of said first wavelength is equal in wavelength to the resonance wavelength for said optical property of one of the turbid medium and the object;
(c) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said first wavelength;
(d) illuminating at least a portion of the turbid medium with substantially monochromatic light of a second wavelength, said illuminated portion of the turbid medium comprising the object;
(e) wherein said substantially monochromatic light of said second wavelength is not equal in wavelength to the resonance wavelength for said optical property of either the turbid medium or the object;
(f) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said second wavelength;
and
(g) using the light detected in steps (c) and (f) to form an image of the object in the turbid medium.

5 more elements

A method of imaging an object in a turbid medium, said method comprising the steps of:

(a) illuminating at least a portion of the turbid medium with substantially monochromatic light of a first wavelength, said illuminated portion of the turbid medium comprising the object, wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said first wavelength comprises a ballistic component, a snake component and a diffuse component;
(b) wherein each of the turbid medium and the object has a resonance wavelength for an optical property, wherein the respective resonance wavelengths for the turbid medium and the object are different and wherein said substantially monochromatic light of said first wavelength is equal in wavelength to the resonance wavelength for said optical property of one of the turbid medium and the object;
(c) preferentially passing from the emergent light the ballistic and snake components thereof;
(d) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said first wavelength, wherein said detecting comprises detecting the preferentially passed light;
(e) illuminating at least a portion of the turbid medium with substantially monochromatic light of a second wavelength, said illuminated portion of the turbid medium comprising the object, wherein the light emergent from the turbid medium following illumination with said substantially monochromatic light of said second wavelength comprises a ballistic component, a snake component and a diffuse component;
(f) wherein said substantially monochromatic light of said second wavelength is not equal in wavelength to the resonance wavelength for said optical property of either the turbid medium or the object;
(g) preferentially passing from the emergent light the ballistic and snake components thereof;
(h) detecting at least a portion of the light emergent from the turbid medium in response to illumination with said substantially monochromatic light of said second wavelength, wherein said detecting comprises detecting the preferentially passed light;
and
(i) using the light detected in steps (d) and (h) to form an image of the object in the turbid medium, wherein said using step comprises using a ratio of the light detected in steps (d) and (h) to form an image of the object in the turbid medium.

7 more elements

Sprectroscopic and time-resolved optical methods and apparatus for imaging objects in turbed media

Life of this patent

Sprectroscopic and time-resolved optical methods and apparatus for imaging objects in turbed media

Life of this patent

Abstract

Claims48