Nasal solution containing a broad spectrum microbicide and a method for its use

A method of reducing the risk of microbial infection and also of combating an established microbial infection which is established first in the nasal mucosa area comprising the application of a nasal spray solution within the nose, said nasal spray solution comprising an aqueous solution having:

• a) from about 0.1 ppmw to 160,000 ppmw sodium bromide sodium iodide or both sodium bromide and sodium iodide;
• b) from about 55 ppmw to 75,000 ppmw of sodium chloride;
• c) from about 0.5 ppmw to about 50,000 ppmw, of sodium hypochlorite;
• d) from about 0.01 wt % to about 5 wt % of glycerin.

A method of reducing the risk of microbial infection and of combating a microbial infection which is established first in the nasal mucosa area comprising the application of a nasal spray solution within the nose, said nasal spray solution A comprising an aqueous solution having:

• a) sodium hypochlorite, potassium hypochlorite, or calcium hypochlorite in a concentration of about 0.5 ppmw to about 50,000 ppmw;
• b) sodium chloride, magnesium chloride, calcium chloride or potassium chloride in a concentration of about 55 ppmw to 75,000 ppmw;
• c) sodium bromide, magnesium bromide, calcium bromide or potassium bromide in a concentration of about 0.7 ppmw to about 140,000 ppmw;
• d) sodium iodide, magnesium iodide, calcium iodide or potassium iodide in a concentration of about 0 1 ppmw to about 160,000 ppmw;
• e) chlorine in a concentration of about 0.4 ppmw to about 50,000 ppmw;
• f) bromine in a concentration of about 1 ppmw to about 75,000 ppmw;
• g) zinc chloride in a concentration of about 0.4 ppmw to about 50,000 ppmw;
• h) zinc bromide in a concentration of about 0.7 ppmw to about 80,000 ppmw;
• and
• i) zinc iodide in a concentration of about 1 ppmw to about 120,000 ppmw;
• and optionally one or more of zinc gluconate in a concentration of about 1.7 ppmw to about 60,000 ppmw, and glycerine or propylene glycol in a concentration of about 0.01 wt % to about 5 wt %.

A method of reducing the risk of microbial infection and of combating a microbial infection which is established first in the nasal mucosa area comprising the application of a nasal spray solution within the nose;

• said nasal spray solution comprising an aqueous solution having:
• from about 0.1 ppmw to about 160,000 ppmw of sodium iodide;
• and
• from about 0.5 ppmw to about 50,000 ppmw of sodium hypochlorite.

A method of reducing the risk of microbial infection and of combating a microbial infection which is established first in the nasal mucosa area comprising the application of a nasal spray solution within the nose, said nasal spray solution comprising an aqueous solution having:

• from about 0.1 ppmw to 160,000 ppmw sodium bromide, sodium iodide, or both sodium bromide and sodium iodide;
• from about 55 ppmw to 75,000 ppmw of sodium chloride;
• from about 0.5 ppmw to about 50,000 ppmw of sodium hypochlorite;
• from about 0.01 wt % to about 5 wt % of glycerin. and
• from about 1.7 ppmw to about 60,000 ppmw of zinc gluconate or zinc bromide.

A method of reducing the risk of microbial infection and of combating a microbial infection which is established first in the nasal mucosa area comprising the application of a nasal spray solution within the nose, said nasal spray solution comprising an aqueous solution having:

• from about 0.4 ppmw to about 75,000 ppmw chlorine or bromine;
• from about 0.1 ppmw to 160,000 ppmw sodium bromide, sodium iodide, or both sodium bromide and sodium iodide;
• from about 55 ppmw to 75,000 ppmw of sodium chloride;
• from about 0.01 wt % to about 5 wt % of glycerin.

A method of reducing the risk of microbial infection and of combating a microbial infection which is established first in the nasal mucosa area comprising the application of a nasal spray solution within the nose, said nasal spray solution comprising an aqueous solution having:

• from about 2 ppmw to about 8,000 ppmw chlorine or bromine;
• from about 140 ppmw to 80,000 ppmw sodium bromide, sodium iodide, or both sodium bromide and sodium iodide;
• from about 250 ppmw to 50,000 ppmw of sodium chloride;
• from about 0.04 wt % to about 2 wt % of glycerin and
• from about 17 ppmw to about 33,000 ppmw of zinc gluconate or zinc bromide.

A nasal spray solution comprising an aqueous solution having the following components:

• a) sodium hypochlorite, potassium hypochlorite, or calcium hypochlorite in a concentration of about 0.5 ppmw to about 50,000 ppmw;
• b) sodium chloride, magnesium chloride, calcium chloride or potassium chloride in a concentration of about 55 ppmw to 75,000 ppmw;
• c) sodium bromide, magnesium bromide, calcium bromide or potassium bromide in a concentration of about 0.7 ppmw to about 140,000 ppmw;
• d) sodium iodide, magnesium iodide, calcium iodide or potassium iodide in a concentration of about 0.1 ppmw to about 160,000 ppmw;
• e) chlorine in a concentration of about 0.4 ppmw to about 50,000 ppmw;
• f) bromine in a concentration of about 1 ppmw to about 75,000 ppmw;
• g) zinc chloride in a concentration of about 0.4 ppmw to about 50,000 ppmw;
• h) zinc bromide in a concentration of about 0.7 ppmw to about 80,000 ppmw;
• and
• i) zinc iodide in a concentration of about 1 ppmw to about 120,000 ppmw;
• and optionally one or more of zinc gluconate in a concentration of about 1.7 ppmw to about 60,000 ppmw, and glycerine or propylene glycol in a concentration of about 0.01 wt % to about 5 wt %.

A nasal spray solution comprising an aqueous solution having:

• a) from about 0.1 ppmw to 160,000 ppmw sodium bromide, sodium iodide or both sodium bromide and sodium iodide;
• b) from about 55 ppmw to 75,000 ppmw of sodium chloride;
• c) from about 0.5 ppmw to about 50,000 ppmw of sodium hypochlorite;
• d) from about 0.01 wt % to about 5 wt % of glycerin.

A nasal spray solution comprising an aqueous solution having:

• from about 0.4 ppmw to about 75,000 chlorine or bromine;
• from about 0.1 ppmw to 160,000 ppmw sodium bromide, sodium iodide, or both sodium bromide and sodium iodide;
• from about 55 ppmw to 75,000 ppmw of sodium chloride;
• from about 0.01 wt % to about 5 wt % of glycerin.

A nasal spray solution comprising an aqueous solution having:

• a) sodium hypochlorite, potassium hypochlorite, or calcium hypochlorite in a concentration of about 0.5 ppmw to about 50,000 ppmw;
• b) sodium chloride, magnesium chloride, calcium chloride or potassium chloride in a concentration of about 55 ppmw to 75,000 ppmw;
• c) sodium bromide, magnesium bromide, calcium bromide or potassium bromide in a concentration of about 0.7 ppmw to about 140,000 A 25 ppmw;
• d) sodium iodide, magnesium iodide, calcium iodide or potassium iodide in a concentration of about 0.1 ppmw to about 160,000 ppmw;
• e) chlorine in a concentration of about 0.4 ppmw to about 50,000 ppmw;
• f) bromine in a concentration of about 1 ppmw to about 75,000 ppmw;
• g) zinc chloride in a concentration of about 0.4 ppmw to about 50,000 ppmw;
• h) zinc bromide in a concentration of about 0.7 ppmw to about 80,000 ppmw;
• and
• i) zinc iodide in a concentration of about 1 ppmw to about 120,000 ppmw;
• and optionally one or more of zinc gluconate in a concentration of about 1.7 ppmw to about 60,000 ppmw, and glycerine or propylene glycol in a concentration of about 0.01 wt % to about 5 wt %.