Stabilized carvedilol injection solution
AssigneeRoche Diagnostics GmbH
InventorsWerner Gruber, Heinrich Woog
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Abstract
Ready-to-use, aqueous injection solutions containing carvedilol (1-(9H-carbazolyl-4-yloxy)-3-[[(2-(2-methoxyphenoxy)ethyl]-amino]-2-propanol) or its pharmacologically harmless salts which are stable in storage and are well tolerated by veins are disclosed.
Claims15
A ready-to-use injection solution comprising carvedilol, or its pharmacologically harmless salts as the active substance, said injection solution at a concentration of 1-5 mg/ml, a physiologically compatible buffer having a pH value of 4 to 7.2, a water-soluble organic solvent in an amount of 5 to 25 wt %, an antioxidant and an agent which binds heavy metal ions.
Dependencies are inferred from the claim text.