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US 6,664,257 B2Granted
Anti-mycobacterial compounds
AssigneeEnzRel Inc.
InventorsMilton B. Yatvin, Richard L. Pederson
Life of this patent
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Abstract
This invention provides compositions of matter, pharmaceutical compounds, methods of synthesizing such compounds and methods for using such compounds to treat animals infected with a pathogenic mycobacterium. The invention specifically provides compositions and pharmaceutical compositions thereof for the treatment of tuberculosis and other Mycobacterium-caused diseases.
Claims16
An antimycobacterial compound that is an inhibitor of a mycobacterium-specific enzyme, wherein the compound has the formula:
- R1 and R2 can each independently be H, lower alkyl (C1 to C10), alkoxy, lower alkyl carboxy, β-lactam, or D- or L-amino acids, or di- or tripeptides, provided that at least one of R1 and R2 are not H.
Dependencies are inferred from the claim text.