Composition and method comprising CPT-11 and a pyrimidine derivative for the treatment of cancer
AssigneeAventis Pharma S.A.
InventorMarie-Christine Bissery
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Abstract
Therapeutic pharmaceutical compositions comprising a pyrimidine derivative in combination with camptothecin or a camptothecin derivative for the treatment of cancer are described. In one embodiment, the pyrimidine derivative is capecitabine and the camptothecin derivative is CPT-11.
Claims6
A synergistic therapeutic pharmaceutical combination comprising an effective amount of CPT-11 in combination with an effective amount of capecitabine, wherein the combination provides a synergistic effect in the in vivo treatment of cancer sensitive to said combination.
A method of treating a cancer by administering to a patient having said cancer a synergistic combination of CPT-11 and capecitabine, wherein said combination provides a synergistic effect in the in vivo treatment of cancer sensitive to said combination.
Dependencies are inferred from the claim text.