Quaternary ammonium salt and process for the preparation thereof
AssigneeToagosei Co., Ltd.
InventorsHiroki Kourai, Shigeyuki Shibata, Katsuyoshi Harada, Masayoshi Kume
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Abstract
The novel quaternary ammonium salt according to the invention has two quaternary ammonium groups connected to a benzene ring, wherein two C4-12 alkyl groups and one C1-2 alkyl group are connected per one nitrogen atom constituting the quaternary ammonium. The compound is used as an antimicrobial agent, exhibits a high safety to human as compared with known antimicrobial agents, exerts an excellent sterilizing effect itself and exhibits a wide sterilizing spectrum. In particular, the compound is used as a presevative for eye drop.
Claims11
A quaternary ammonium salt represented by the following general formula (1):
- wherein R1 and R2 each represent a C4-12 alkyl group and may be the same or different;
- R3 represents a C1-2 alkyl group;
- k represents an integer of from 0 to 4;
- X represents an inorganic or organic anion group;
- n represents the valence of the anion group X which is selected from 1 and 2;
- and m represents an integer of 2 when n is 1 or 1 when n is 2.
Dependencies are inferred from the claim text.