Arrays with mask layers and methods of manufacturing same
Assignee3M Innovative Properties Company
InventorsSanjay L. Patil, Kurt J. Halverson, Robin E. Wright
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Abstract
The present invention provides high-density arrays including mask layers and methods of manufacturing the same. The arrays are formed on a polymeric substrate and include a mask layer. Various linking agents, linking agent coatings, and/or reactants may be provided on the mask layer. Where present, the linking agents and reactants preferably operate together to capture a desired analyte which can then be detected based on an electromagnetic signal, e.g., fluorescence, that is emitted by the analyte in response to excitation energy incident on the array. With the mask layer in place, the signal-to-background ratio provided by the arrays can be increased.
Claims12
An array comprising:
- a polymeric substrate comprising a relaxed oriented film or a relaxed elastomeric material, the substrate having a surface;
- a mask layer on said surface, the mask layer comprising ink and linking agents wherein the mask layer has a projected surface area and a topographical surface area wherein the topographical surface area is greater than the projected surface area;
- and at least one reactant affixed to one or more binding sites within the mask layer.
Dependencies are inferred from the claim text.