Iontophoresis, electroporation and combination patches for local drug delivery to body tissues
AssigneeGMP Drug Delivery, Inc.
InventorsNeville Crawford, Charles L. Brown, III
Life of this patent
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Abstract
Patch-based devices for enhancing the local delivery of drugs, pharmaceuticals, plasmids, genes and other agents into the tissues of the living body. The patch devices provide an electrical driving force that can increase the rate of migration of drugs and other therapeutic agents out of a polymer matrix into body tissues and cells using iontophoresis only, electroporation only, or combined inontophoresis and electroporation. The two procedures may be applied sequentially in any order without removing or repositioning the patch.
Claims20
A patch-based device for enhancing the local delivery of a treatment agent into target tissues comprising:
- a patch base having a tissue facing surface and a reservoir facing surface;
- an iontophoresis and electroporation electrode network comprising a plurality of electrodes arranged in a spaced parallel pattern on the tissue facing surface of the patch base;
- and
- a treatment agent reservoir on the reservoir facing surface of the patch base in fluid communication with the tissue facing surface of the patch base and the electrode network.
Dependencies are inferred from the claim text.