Production of optically active α-hydroxyacetals
AssigneeSolvias AG
InventorMartin Studer
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Abstract
A process for the heterogeneous and enantioselective hydrogenation of prochiral organic α-keto compounds with platinum as the catalyst in the presence of a soluble or immobilized chiral aromatic nitrogen base with at least one basic nitrogen atom adjacent to stereogenic carbon atoms, whereby prochiral α-ketoacetals are hydrogenated to optically active α-hydroxyacetals.
Claims11
Process for the heterogeneous and enantio-selective hydrogenation of prochiral organic α-keto compounds with platinum as the catalyst and in the presence of a soluble or immobilised chiral aromatic nitrogen base with at least one basic nitrogen atom adjacent to stereogenic carbon atoms, whereby prochiral α-ketoacetals are hydrogenated to optically active α-hydroxyacetals.
Dependencies are inferred from the claim text.