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US 6,660,873 B2Granted
Method for the preparation of citalopram
AssigneeH. Lundbeck A/S
InventorsHans Petersen, Robert Dancer
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Abstract
A method for the preparation of citalopram comprising reaction of a compound of formula 5-aminomethyl-1-(3-dimethylamino-propyl)-1-(4-fluoro-phenyl)-1,3-dihydro-isobenzofuran with an oxidising agent to prepare citalopram.
Claims21
A method for the preparation of citalopram comprising reacting a compound of Formula IV
- with an oxidising agent to afford citalopram
- which is isolated as the base or a pharmaceutically acceptable salt thereof.
A compound of Formula V
Dependencies are inferred from the claim text.