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US 6,660,810 B1Granted
Non cross-linked block polyetherester, preparation and uses
AssigneeDebio Recherche Pharmaceutique S.A.
InventorsPaolo Ferruti, Piero Orsolini
Life of this patent
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Abstract
The present invention relates to a non crosslinked block polymer. It also relates to a process for the preparation thereof and to the use thereof particularly in pharmaceutical compositions. The block polymer according to the invention contains sequences of polyethylene glycol linked to sequences of polyester and/or polycarbonate. The polyester sequences are selected in particular from polyfumarate, polymaleate and polysuccinate sequences.
Claims3
Non crosslinked block polymer having the general formula (I)
- [—Pa—(Pb—Pc)s—Pa′—Pd—Pe]z
- wherein:
- z=1 to 20,
- S=0 to 25,
- Pa represents:
- —[COA—COOB]t—
- where:
- t=1 to 150, and
- A represents CH═CH or CH2—CH2
- B represents (CH2)n—O— where n=1 to 7,
- Pb represents —[COO]—x where x=0 or 1,
- Pd represents:
- —[COO]y—
- where y=0 or 1
- provided that if s=0 or x=0 then y=1, and if y=0 then s≠0 and x=1;
- Pc and Pe, each independently of one another, represent:
- [RO]u
- where:
- u=4 to 150, and
- R represents an alkylidene,
- Pa′ represents —[COA—COOB′]—t
- where A has the same meaning as above
- B′ represents (CH2)n′O, where n′=1 to 7, and t′=0 to 150 the weight-average molecular mass of the polymer being in the range 2,000 daltons to 300,000 daltons.
20 more elements
Dependencies are inferred from the claim text.