Pesticidal activity of functionalized alkenes
AssigneeNorth Carolina State University
InventorsRussell J. Linderman, R. Michael Roe, Deborah M. Thompson, Matthew Vanderherehen
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Abstract
The present invention provides non-peptide organic compounds that have a structure analogous to or reminiscent of the TMOF structure and have pesticidal activity. Thus the present invention concerns pesticidal compounds that inhibit digestion in pests by terminating or otherwise blocking synthesis of digestive enzymes by activating a TMOF receptor (collectively referred to herein as “pesticidal compounds”). The pesticidal compounds and other compounds of the present invention are usefully employed in the control of pests, particularly insect pests such as mosquitoes, which ingest blood.
Claims43
A method for controlling a pest, comprising administering to said pest a compound of formula I:
- wherein:
- X is selected from the group consisting of —CHCH—, —CH2CH2—, and —CC—;
- Z is selected from the group consisting of —OH, —NH2 and —OR6 wherein R6 is loweralkyl;
- m≧0 and n≧1 and together total an integer from 1 to 12;
- the ring bearing substituents R1, R2, R3, R4 and R5 is a phenyl ring;
- and
- R1, R2, R3, R4, and R5 are each independently selected from the group consisting of —H, —OH, halo, loweralkyl, loweralkoxy and phenyl;
- subject to the proviso that:
- a pair of R1 and R2, R2 and R3, or R3 and R4 on the phenyl ring may together represent —CR7═CR8—CR9═CR10—, to form with the phenyl ring of formula I a naphthyl ring system, wherein R7, R8, R9, and R10 are each independently selected from the group consisting of —H, —OH, halo, loweralkyl, and loweralkoxy;
- and wherein said administering step is carried out by applying said compound of formula I to a subject or substrate from which said insect is to be repelled in an amount sufficient to repel said insect.
Dependencies are inferred from the claim text.