Coumarin compounds as microtubule stabilizing agents and therapeutic uses thereof
AssigneeThe Regents of the University of California
InventorsRobert S. Jacobs, Leslie Wilson, Hamta Madari
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Abstract
Compounds and compositions for stabilizing microtubules are disclosed. Also disclosed are methods of inhibiting, preventing, regulating, modulating, attenuating, stabilizing, or affecting microtubule formation or function. Methods of treating, preventing or inhibiting diseases and disorders associated with microtubule formation, function, or both by administering a microtubule stabilizing agent such as coumarin is also disclosed.
Claims23
A method of stabilizing microtubules in a subject comprising administering at least one coumarin compound or a derivative thereof to the subject.
A method of modulating microtubules in a subject comprising administering at least one coumarin compound or a derivative thereof to the subject.
Dependencies are inferred from the claim text.