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US 6,660,523 B2Granted
Dendritic cells; methods
AssigneeSchering Corporation
InventorsBianca Blom, Yong-Jun Liu
Life of this patent
Estimating the term…
Abstract
Dendritic cell subsets, and various methods of making and using same are provided. In particular, methods for making a defined subset of dendritic cells are provided.
Claims7
A method of producing IPC comprising contacting CD34++CD45RA-early heamatopoietic progenitor cells for at least 13 days with an effective amount of a combination of FLT3-Ligand and TPO wherein:
- (a) the progenitor cells accumulate within 24 hrs, at least 5000 pg IFN per 20,000 IPC after viral stimulation;
- and (b) the IPC number at least 1×107.
Dependencies are inferred from the claim text.