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US 6,660,313 B2Granted
Stable lactase tablets
AssigneeMcNeil-PPC, Inc.
InventorsSunanda R. Kulkarni, Robert T. McFadden, David H. Rogers, James T. Walter, Jr.
Life of this patent
Estimating the term…
Abstract
There is a formulation having improved chemical stability comprising: a) from about 1% to about 20% by weight of a combination of lactase and cutting agent where said combination has from 0 to about 4 parts by weight cutting agent for each part by weight lactase; b) from about 1% to about 98% by weight of microcrystalline cellulose; c) from about 0% to about 97% by weight of mannitol; and d) an effective amount of lubricant to aid compression.
Claims7
A formulation comprising:
- a) from about 1% to about 20% by weight of a combination of lactase and cutting agent where said combination has from 0 to about 4 parts by weight cutting agent for each part by weight lactase;
- b) from about 1% to about 98% by weight of microcrystalline cellulose;
- c) from about 0% to about 97% by weight of mannitol;
- and
- d) an effective amount of lubricant to aid compression.
2 more elements
A formulation comprising:
- a) from about 9.6% to about 12% by weight of a combination of lactase and cutting agent where said combination has about 1 part by weight cutting agent for each part by weight lactase;
- b) about 30% by weight of microcrystalline cellulose;
- c) from about 57% to about 59.4% by weight of mannitol;
- and
- d) an effective amount of lubricant to aid compression.
2 more elements
Dependencies are inferred from the claim text.