Paroxetine tablets and capsules
AssigneePentech Pharmaceuticals, Inc.
InventorsBruce Ronsen, Venkata R. Kota, Yogesh Sadhale
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Abstract
Method for preparing a wet granule formulation of paroxetine hydrochloride are disclosed. The formulations are suitable for tabletting and capsulation.
Claims20
A method to prepare a formulation of paroxetine hydrochloride suitable for tabletting and encapsulation which method comprises sizing a dried mixture of (a) at least one filler and (b) an aqueous solution comprising paroxetine hydrochloride at a concentration of at least 150 mg/ml and a combination of an acidulant and a water dispersible polymer, said combination present in an amount effective to solubilize sufficient paroxetine hydrochloride to include an adequate dose of paroxetine hydrochloride with an amount of filler suitable for encapsulation or tabletting.
Dependencies are inferred from the claim text.