Transdermal drug delivery device package with improved drug stability
AssigneeAlza Corporation
InventorsTyler Watanabe, Robert M. Gale
Life of this patent
Estimating the term…
Abstract
This invention relates to the field of transdermal drug delivery devices and more particularly to improved storage stability thereof. The invention comprises providing a transdermal drug delivery device with a non-occlusive backing or release liner in combination with a degradation protectant such as a desiccant or oxygen scavenger within the sealed pouch containing the device. The combination of the present invention provides increased shelf-life of these devices.
Claims16
A package for a transdermal drug delivery device comprising, in combination:
- a pouch containing:
- (a) a transdermal drug delivery device comprising a drug reservoir layer positioned between a release liner and a backing layer, at least one of said release liner and said backing layer being non-occlusive;
- (b) a degradation protectant.
A method for preventing degradation of a transdermal drug delivery device of the type comprising a drug reservoir positioned between a backing layer and a release liner comprising:
- (a) providing the transdermal drug delivery device with a non-occlusive backing layer or release liner comprising a moisture vapor transmission rate of at least 20 g/m2.24 hr;
- (b) placing a degradation protectant within a pouch;
- (c) placing the device within the pouch;
- (d) sealing the pouch.
A method for increasing the shelf-life of a transdermal drug delivery device of the type comprising a drug reservoir positioned between a backing layer and a release liner comprising:
- (a) providing the transdermal drug delivery device with a non-occlusive backing layer or release liner comprising a moisture vapor transmission rate of at least 20 g/m2.24 hr r;
- (b) placing a degradation protectant within a pouch;
- (c) placing the device within the pouch;
- (d) sealing the pouch.
Dependencies are inferred from the claim text.