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US 6,659,985 B2Granted
Method to use transdermal administration of androgens to the adnexa of the eye
AssigneeSouthern College of Optometry
InventorCharles Gerald Connor
Life of this patent
Estimating the term…
Abstract
This invention relates to a method for treating dry eye or increasing contact lens wear time through the transdermal delivery of androgenic hormones to the adnexa of the eye. More specifically, an androgenic hormone such as testosterone or dehydroepiandrosterone is solubilized in pharmaceutically effective carrier such as a facial cream or gel. The androgenic hormone in a pharmaceutically effective carrier is applied to the adnexa of the eye, which is the tissue adjacent to and surrounding the eyeball.
Claims15
A method of treating dry eye disease comprising:
- (a) transdermally administering a composition to a subject in need of such treatment, said composition comprising a therapeutically effective amount of an androgenic hormone in a pharmaceutically effective carrier wherein said transdermally administering involves administering said compound to the adnexa of the eye of said subject and said androgenic hormone comprised between 1 to 5% by weight of said pharmaceutically effective carrier.
A method to increase contact lens wear time comprising:
- (a) transdermally administering a composition to a subject in need of such treatment, said composition comprising a therapeutically effective amount of an androgenic hormone in a pharmaceutically effective carrier, wherein said transdermally administering involves applying said compound to the adnexa of the eye of said subject.
Dependencies are inferred from the claim text.