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US 6,659,949 B1Granted
Technique to measure capillary related interstitial fluid using ultra-sonic methods and devices
OwnerPhilipp Lang, John D. Mendleininventors
Life of this patent
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Abstract
The present invention provides for methods and devices for monitoring capillary related interstitial thickness. The invention also includes methods of measuring capillary related interstitial fluid, as well as cardiac, vascular, renal and hepatic function. Specific devices, particularly probes, are provided for such methods.
Claims11
A method of detecting rapid changes in capillary related interstitial fluid volume in a human, comprising:
- a) positioning a first ultrasound probe on a skin surface of a first anatomical region of said human in need of capillary related interstitial fluid volume detection during a clinically relevant fine period,
- b) interrogating said first anatomical region with ultrasound pulses from said first ultrasound probe, and
- c) detecting a first capillary related interstitial fluid volume between an inner surface of skin and either a bone or fat surface in said first anatomical region with ultrasound signals from said ultrasound pulses, wherein said first capillary related interstitial fluid volume is an indicator of capillary related interstitial fluid volume of said first anatomical region or is an indicator of systemic capillary related interstitial fluid volume.
Dependencies are inferred from the claim text.