Method for immobilizing and/or crystallizing biological macromolecules on carbon nanotubes and uses
AssigneesCommissariat a l'Energie Atomique, Centre National de la Recherche Scientifique (CNRS)
InventorsFabrice Balavoine, Charles Miokowski, Patrick Schultz, Cyrille Richard
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Abstract
Method for the attachment and/or crystallization of macromolecules, chemical reagents used in the said method, products obtained as well as applications of the said products in the field of materials and of structural biology, in particular as biosensors or as biomaterials. The said method comprises essentially the incubation, without stirring, for at least 15 minutes, of a biological macromolecule in solution with nanotubes of carbon closed at their ends, under suitable temperature and pH conditions.
Claims12
A method for the attachment of proteins to, and crystallization of proteins on carbon nanotubes comprising:
- preparing a solution of said proteins in an aqueous or aqueous-alcoholic solvent at a pH ranging from 5.5 to 8.5, and
- contacting without stirring nanotubes of carbon, which are closed at their ends, with said solution for 15 minutes to 48 hours at room temperature.
Dependencies are inferred from the claim text.