Hybridization buffers using low molecular weight dextran sulfate and methods for their use
AssigneeVentana Medical Systems, Inc.
InventorsJoseph Utermohlen, Catherine Wolf, Kimberly Christensen
Life of this patent
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Abstract
The invention is directed to an improvement in automated tissue staining system having evaporation inhibitor liquid covering the polynucleotide hybridization buffer-covered tissue on a slide, wherein the improvement comprises a polynucleotide hybridization buffer for in situ hybridization comprising a low molecular weight dextran sulfate having a molecular weight range from about 8,000 to about 16,000.
Claims4
In an automated tissue staining system having evaporation inhibitor liquid covering the polynucleotide hybridization buffer-covered tissue on a slide, wherein the improvement comprises a polynucleotide hybridization buffer for in situ hybridization comprising a low molecular weight dextran sulfate having a molecular weight range from about 8,000 to about 16,000.
Dependencies are inferred from the claim text.