Attenuated live neospora vaccine
AssigneePfizer Inc.
InventorsDavid A Brake, Byron L Blagburn, David S Lindsay
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Abstract
The present invention provides attenuated live cultures of the pathogenic protozoan parasite, Neospora, and live vaccines against neosporosis prepared therefrom which are useful in the prevention of clinical disease and abortion in mammals.
Claims8
A live culture of cells of an attenuated strain of a species of Neosyora, wherein the strain is NCTS-8 which is present in MARC145 monkey kidney cells having ATCC accession No. CRL12230.
A vaccine for protecting a mammal against neosporosis, comprising an immunologically effective amount of live cells of an attenuated strain of a species of Neosyora and a veterinarily acceptable carrier, wherein the strain is NCTS-8 which is present in MARC145 monkey kidney cells having ATCC accession No. CRL12230.
A combination vaccine, comprising an immunologically effective amount of live cells of a an attenuated strain of a species of Neospora and a veterinarily acceptable carrier, wherein the strain is NCTS-8 which is present in MARC145 monkey kidney cells having ATCC accession No. CRL12230.
A composition comprising a veterinarily acceptable carrier and an immunologically effective amount of live cells of an attenuated strain of a species of Neosyora, wherein the strain is NCTS-8 which is present in MARC145 monkey kidney cells having ATCC accession No. CRL12230.
Dependencies are inferred from the claim text.