Occlusion device with non-thrombogenic properties
AssigneeCardia, Inc.
InventorsMichael P. Corcoran, Peter M. Buonomo, Joseph A. Marino
Life of this patent
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Abstract
A method of forming a PVA foam structure for use in an occlusion device such that the PVA foam structure comprises non-thrombogenic properties. The method comprises forming a PVA gel and incorporating heparin into the PVA gel. The PVA foam structure is then treated with the PVA gel and heparin mixture, such as by soaking the PVA foam structure in the gel.
Claims33
A method of creating a non-thrombogenic polyvinyl alcohol foam structure for use in an occlusion device, the method comprising:
- forming a structure from polyvinyl alcohol foam;
- applying a mixture comprising polyvinyl alcohol and heparin chemically bonded to the polyvinyl alcohol to the polyvinyl alcohol foam structure;
- and
- attaching the foam structure to an occlusion device.
A method of forming a polyvinyl alcohol foam structure having non-thrombogenic properties for use in an occlusion device, the method comprising:
- creating a polyvinyl alcohol mixture comprising polyvinyl alcohol and heparin bonded to the polyvinyl alcohol;
- applying the polyvinyl alcohol heparin mixture to the polyvinyl alcohol foam structure;
- and
- attaching the polyvinyl alcohol foam structure to an occlusion device.
An occlusion device comprising a polyvinyl alcohol foam structure having non-thrombogenic properties, the polyvinyl alcohol foam structure comprising:
- a polyvinyl alcohol foam substrate;
- a mixture comprising polyvinyl alcohol and heparin chemically bonded to the polyvinyl alcohol applied to the polyvinyl alcohol foam substrate.
An occlusion device, the device comprising:
- a center section extending in an axial direction;
- upper and lower elastic shape memory fixation devices emanating from the center section;
- and
- first and second foam sheets attached to the upper and lower fixation devices, respectively, wherein the foam sheets are formed of polyvinyl alcohol foam which has been treated with a mixture comprising polyvinyl alcohol and heparin chemically bonded to the polyvinyl alcohol.
An occlusion device for the closure of a physical anomaly, the device comprising:
- a support structure including a center section and first and second flexible arms extending outward from the center section;
- and
- a first foam sheet attached to the first flexible arm, wherein the first foam sheet is formed of polyvinyl alcohol foam which has been treated with a polyvinyl alcohol gel comprising polyvinyl alcohol and heparin chemically bonded to the polyvinyl alcohol.
An occlusion device, the device comprising:
- a center strut;
- a first plurality of fixation devices extending from a first end of the center strut;
- a first sheet attached to the first plurality of fixation devices, wherein the first sheet is formed of polyvinyl alcohol foam which has been treated with a mixture comprising polyvinyl alcohol and heparin chemically bonded to the polyvinyl alcohol;
- and
- a second plurality of fixation devices extending from a second end of the center strut.
An occlusion device, the device comprising:
- a center strut having distal and proximal ends;
- a first set of stranded wire support arms extending from the distal end of the center strut;
- a first sheet attached to the first set of arms, wherein the first sheet is formed from polyvinyl alcohol foam which has been treated with a polyvinyl alcohol gel comprising polyvinyl alcohol and heparin chemically bonded to the polyvinyl alcohol;
- a second set of stranded wire support arms extending from the proximal end of the center strut;
- and
- a second sheet attached to the second set of support arms, wherein the second sheet is formed from polyvinyl alcohol foam which has been treated with a polyvinyl alcohol gel comprising polyvinyl alcohol and heparin chemically bonded to the polyvinyl alcohol.
An occlusion device for the closure of a physical anomaly, the occlusion device comprising:
- a center piece extending in an axial direction;
- first and second collapsible support frames spaced from one another and emanating from the center piece, the support frames being formed by multiwire strands;
- and
- first and second foam sheets attached to the first and second collapsible support frames, respectively, wherein the sheets are formed from polyvinyl alcohol foam which has been treated with a mixture comprising polyvinyl alcohol and heparin chemically bonded to the polyvinyl alcohol.
An occlusion device, the device comprising:
- a first collapsible support frame;
- a second collapsible support frame, the second collapsible support frame being spaced from and connected to the first collapsible support frame;
- a first sheet attached to the first collapsible support frame, wherein the first sheet is formed from polyvinyl alcohol foam which has been treated with a mixture comprising polyvinyl alcohol and heparin chemically bonded to the polyvinyl alcohol;
- and
- a second polyvinyl alcohol sheet attached to the second collapsible support frame, wherein the second sheet is formed from polyvinyl alcohol foam which has been treated with a mixture comprising polyvinyl alcohol and heparin chemically bonded to the polyvinyl alcohol.
An occlusion device, the device comprising:
- a support structure;
- and
- a polyvinyl alcohol foam occlusion member attached to the support structure wherein the occlusion member is formed from polyvinyl alcohol foam which has been treated with a mixture comprising polyvinyl alcohol and heparin chemically bonded to the polyvinyl alcohol.
A method of creating foam sheets for use in an occlusion device wherein the foam sheets have non-thrombogenic properties, the method comprising:
- providing polyvinyl alcohol foam;
- slicing the foam into sheets of a desired size;
- dipping the foam sheets into a solution comprising a thrombosis inhibitor;
- and
- attaching the foam sheets to an occlusion device.
A method of creating foam with non-thrombogenic properties for use in an occlusion device, the method comprising:
- forming a mixture of polyvinyl alcohol and heparin in a liquid state;
- forming a foam of the polyvinyl alcohol and heparin mixture;
- and
- attaching the foam to an occlusion device.
Dependencies are inferred from the claim text.