Dual surface protection coating for drug delivery balloon catheters and stents

A catheter for drug delivery comprising:

• a longitudinally extending shaft having a distal end and a proximal end, the shaft defining an inflation lumen;
• a balloon member having an exterior surface disposed proximate the distal end of said shaft in fluid communication with said inflation lumen, said balloon member expandable from a first position, wherein said balloon member is sized for intravascular insertion, to a second position, wherein at least a portion of said exterior surface contacts a vessel wall;
• a first coating disposed over at least a portion of said exterior surface of said balloon member, said first coating comprising a therapeutic substance;
• and
• a second coating overlying at least a substantial portion of said first coating when said balloon member is in said first position, wherein said second coating comprises a relatively inelastic material so that said second coating fractures in response to expansion of said balloon member to said second position to allow elution of said therapeutic substance through fissures formed in said second coating.