Database system including computer code for predictive cellular bioinformatics

A computer program product for populating a database with information related to an effect of a manipulation on a plurality of cells from a plurality of different cell lines, wherein said cells are from a plurality of sites in a spatial orientation, each of the sites being capable of holding a plurality of cells to be imaged, said computer program product comprising:

• code for receiving, from said plurality of sites, a site at a time, one or more images of a plurality of components from a plurality of cells from a plurality of different cell lines. wherein said plurality of cells are in a plurality of stages of the cell cycle, said stages of the cell cycle including at least one selected from interphase, G0 phase, G1 phase, S phase, G2 phase, M phase, prophase, prometaphase, metaphase, anaphase, and telophase and wherein said plurality of cells have been exposed to said manipulation;
• code for determining from said images of said manipulated cells a plurality of features of said plurality of components from said plurality of cells for each of said plurality of different cell lines
• code for determining a plurality of descriptors for each of said plurality of different cell lines by combining said plurality of features for each of said plurality of different cell lines;
• code for statistically analyzing said plurality of descriptors to determine the effect of said manipulation on said plurality of cells of said plurality of different cell lines;
• code for populating a database with said descriptors and said statistical analysis;
• and
• a computer readable storage medium for holding the codes.