Ultrasound driven devices for accelerated transfer of substances across porous boundaries

Abstract

A method of phonophoretic transfer of an active agent into or across a porous surface, which method comprises contacting the active agent with the porous surface and applying thereto ultrasound at a frequency of between 20 kHz and 3 MHz; characterised in that the active agent is ideally cationic and is disposed in a low viscosity carrier and wherein the active agent is in direct contact with the porous surface. An apparatus for phonophoretic transfer of an active agent to or through a porous surface, said apparatus comprising an ultrasonic generator, a housing provided with an ultrasound transducer mounted in or on housing, and a treatment chamber disposed in or on said housing, said transducer being directed towards said treatment chamber, wherein the treatment chamber is provided with a liquid-tight membrane to retain the active agent against a porous surface located in the treatment chamber during sonication.

Dependencies are inferred from the claim text.