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AssigneeCornell Research Foundation, Inc.
InventorsMilton Zaitlin, Daniel Golemboski, George Lomonossoff
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The invention described herein discloses a virus-induced resistance that may be transferred from one plant generation to another in which transgenic plants containing a coding sequence, taken from the read-through portion of the replicase portion of the viral genome, are resistant to subsequent disease by the virus. The use of the 54 kDa coding sequence from TMV is described as a specific example of the broader technology. Thus, the invention defines a means for bringing about viral resistance in plants which have been transformed with nucleic acid copies of fragments or segments taken from the replicase portion of the pathogenic virus genome. In addition, the present invention defines transformed plants and their seeds which carry a portion of the viral genome which encodes for a portion of the read-through portion of the replicase genome of the pathogenic virus.
A DNA molecule comprising in operable linkage:
A transgenic plant cell transformed with a DNA molecule encoding a replicase protein or polypeptide from a plant pathogenic virus.
A transgenic plant transformed with a DNA molecule encoding a replicase protein or polypeptide from a plant pathogenic virus.
A transgenic plant seed transformed with a DNA molecule encoding a replicase protein or polypeptide from a plant pathogenic virus.
A method of imparting disease resistance to a plant cell comprising:
Dependencies are inferred from the claim text.