Aspartyl dipeptide ester derivatives and sweeteners
AssigneeAjinomoto Co., Inc.
InventorsYusuke Amino, Tadashi Takemoto, Kazuko Yuzawa, Ryoichiro Nakamura
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Abstract
Aspartyl dipeptide ester derivatives, such as a N-[N-[3-(3,4-dihydroxyphenyl)-3-methylbutyl]-L-α-aspartyl]-L-phenylalanine 1-methyl ester, or salts thereof, having a high degree of sweetness compared to conventional sweeteners. These derivatives are excellent in sweetening potency and may be used as sweetener components in products such as foods and drinks. They may also be used as low calorie sweeteners and in methods of sweetening products. Foods and drinks comprising these derivatives as well as methods for their production.
Claims28
An aspartyl dipeptide ester derivative, or a salt thereof, represented by the following formula (1):
- wherein R1, R2, R3, R4 and R5, independently from each other, represent a hydrogen atom or a hydroxyl group, at least any two of R1 to R5 are hydroxyl groups, and R6 and R7, independently from each other, represent a hydrogen atom or an alkyl group having 1 to 3 carbon atoms.
A method for making a compound of formula (1):
- wherein:
- R1, R2, R3, R4 and R5, each independently represent a hydrogen atom or a hydroxyl group,
- at least two of R1 to R5 are hydroxyl groups, and
- R6 and R7, each independently represent a hydrogen atom or an alkyl group having 1 to 3 carbon atoms;
- comprising:
- reductively alkylating aspartame with a 3-phenylpropionaldehyde or cinnamaldehyde derivative and a reducing agent.
Dependencies are inferred from the claim text.